synlayer
The evidence layer for clinical judgment

Evidence, synthesized.

synlayer builds the evidence layer for clinical judgment: products that read what clinicians already have, synthesize the evidence, and cite every line.

Guideline§4.2 · Diagnostic work-up
Systematic reviewTbl 2 · Pooled outcomes
Cohort studyResults · Sensitivity
The case in front of youHistory · labs · reports
Synthesized · illustrative

Consider the condition first. The deciding test is not yet in the case.

Each sentence links to the passage it came from. A sentence with no source is removed before anyone sees it.

Products

One evidence engine, two products

Each product serves different clinicians and is paid for by different organizations. Both run on the same engine and make the same promise.

cense
Make sense of the rare.

Cense gives every physician the clinical sense of a rare-disease specialist: a ranked differential where every line is cited.

For
Licensed physicians, free
Paid by
Rare-disease centers, diagnostic labs, medical-affairs teams
Scope
10 rare diseases at launch, 28 by 2028
Status
Physician pilot with rare-disease centers, 2027
Visit Cense →
grovera
Know what's working.

Grovera shows families and clinicians what the evidence says about each intervention, and whether this child is actually changing.

For
Developmental pediatricians, child psychiatrists and neurologists; families. Free
Paid by
ABA and developmental centers, payers, medical-affairs teams
Scope
Autism and ADHD first; four more conditions by 2028
Status
In development; clinician pilot with US centers, 2027
Visit Grovera →
Why these two

Two problems that look different and are shaped the same

In both, the knowledge exists. It does not reach the moment of decision.

Rare disease · Cense

Rare to each physician, common together. Patients wait years for a name.

4.7 yrsaverage time to a confirmed diagnosis
6 in 10first misdiagnosed with another condition
Pediatric neurodevelopment · Grovera

Many interventions for each family, hard to compare. Progress is often measured by feel.

1 in 31US 8-year-olds identified with autism
7.1MUS children ever diagnosed with ADHD
  1. L1 · Faye F, et al. Time to diagnosis and determinants of diagnostic delays of people living with a rare disease. Eur J Hum Genet. 2024. Rare Barometer survey, n > 10,000, 42 countries, 2022.
  2. L2 · Shaw KA, et al. Prevalence and early identification of autism spectrum disorder among children aged 4 and 8 years. MMWR Surveill Summ. 2025;74(2). ADDM Network, 2022 data.
  3. L3 · Danielson ML, et al. ADHD prevalence among U.S. children and adolescents in 2022. J Clin Child Adolesc Psychol. 2024.
The engine

What both products share

A second product line mostly costs clinical content, not a new technology stack.

How the engine works →
CenseRare-disease differential
GroveraIntervention evidence and outcomes
synlayer Evidence Engine Knowledge packs Retrieval and citation checker Reasoning orchestration Evaluation and release gates Outcomes engine 2027
Foundation models · third-party, replaceable, cite only the evidence layer
Compliance base · HIPAA, credential checks, audit, version log
Our promise, in both products

No citation, no claim.

  • Every line citedAny sentence that cannot be matched to a source passage is removed.
  • Clinicians decideOur products give a considered opinion with its basis. Diagnosis and care plans stay with clinicians and, in Grovera, families.
  • Decision support by designBuilt to the FDA's January 2026 criteria for non-device clinical decision support. Parent-facing content is general information.
  • IndependentNo drug brands, no doses, sponsorship disclosed. synlayer is not affiliated with any platform, health system or drug company.
Roadmap

Two products on one schedule

Both products are reviewed at the same two gates. A product that misses its gate does not move to the next phase.

Now to 2027-05 Gate 1 · 2027-05 → 2027-11 Gate 2 · 2027-11 → 2028-11 Cense
Physician app
10 diseases, center pilot
Centers and API
20 diseases
28 diseases, EHR sidebar
New languages and regions
Grovera
Evidence map and plan review
Autism and ADHD, center pilot
Outcomes, Clinics, Family
First payer pilot
Four more conditions
Regions alongside Cense

Dates are approximate. Both products launch in the United States, in English, from a single US deployment.

Work with us

Physicians and rare-disease centersRequest Cense early access → Clinicians, centers and payersRequest Grovera early access → Investors, partners, pressContact synlayer →